
Inform medical staff if you have ever experienced a hypersensitivity to this type of medication before or if you have any heart conditions that may require closer monitoring after the administration of a Zofran Injection. Your doctor can determine if Zofran Injection is right for your situation. Discuss other medical conditions and allergies with your doctor and list any Rx drugs you currently take or use, including OTC products, herbal remedies, and vitamin or dietary supplements. Some patients have a reaction to sedation and can become nauseous and vomit during recovery which can interfere with the surgery that was just performed unless a Zofran Injection has been given.Īsk your doctor if a Zofran Injection is safe if given while you are pregnant or breast feeding. Some patients are administered a Zofran Injection pre-operatively if they are to undergo any surgery that involves the abdomen, back, throat, or any part of the body that is affected by the force of vomiting. PONV stands for post-operative nausea and vomiting, another reason for a Zofran Injection.

The generic alternative is not manufactured by the company that makes the brand product. Vomiting at such a young age may be considered a risk due to the possibility of the child aspirating. Patients as young as 6 months may be administered a Zofran Injection or generic Ondansetron to help prevent emetic symptoms. As long as the signals to your vomit center are blocked, you will not become nauseous and throw up due to the chemo drugs. As it reaches your bloodstream, it is carried to your brain and blocks the action of a neurotransmitter called serotonin, which is responsible for sending the vomit signals. It is usually administered intravenously slowly about 30 minutes before chemotherapy begins.

Zofran Injection is a 5-hydroxytryptamine receptor antagonist, or more simply, a 5-HT3 RA. Many cancer patients can handle the other effects of the chemotherapy, but dread being sick and throwing up.īlock the Brain Chemical Responsible for Signaling Your Vomit Center This is the reason for side effects such as nausea and vomiting. Cancer drugs are given to kill the fast growing cancer cells in your body, but because healthy cells also grow rapidly, the drugs kill those as well. A Zofran Injection may be recommended as a preventive measure when you start chemotherapy so you do not become nauseous or vomit.
